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冠状动脉搭桥手术后早期出院:是否安全?

Early discharge following coronary bypass surgery: is it safe?

作者信息

Loubani M, Mediratta N, Hickey M S, Galiñanes M

机构信息

Division of Cardiac Surgery, Department of Surgery, University of Leicester, Glenfield Hospital, LE3 9QP, Leicester, UK.

出版信息

Eur J Cardiothorac Surg. 2000 Jul;18(1):22-6. doi: 10.1016/s1010-7940(00)00467-x.

Abstract

OBJECTIVES

Early discharge has been proposed as a means of containing the escalating cost of health care in cardiac surgery. The aim of this study was to investigate whether shortening the length of hospital stay after coronary artery bypass surgery is safe and cost effective.

METHODS

Patients (n=198) undergoing elective bypass surgery by two surgeons for a period of 12 months were prospectively entered into the study but not randomized. The anaesthetic and surgical treatments were identical in all patients with the exception that one of the surgeons used intermittent cold crystalloid cardioplegia ('normal discharge' group; n=119) and the other used intermittent ischaemia without cardioplegia ('early discharge' group; n=79). Previous to the study both surgeons discharged patients on the 7th-8th postoperative day. For the present study, one of the two surgeons adopted the new policy of discharging patients on the 4th postoperative day ('early discharge' group). The criteria for hospital discharge included: presence of sinus rhythm, absence of pyrexia and wound infection, normal routine blood tests, satisfactory chest X-ray and ECG and full mobility.

RESULTS

The clinical characteristics were identical in the two groups. The number of grafts per patient was 2.8+/-0.8 and 3.2+/-1.0, and the total ischaemic time 47+/-13 and 46+/-14 min in the normal and early discharge groups, respectively (P=NS in each instance). In the normal discharge group the mean hospital stay was 7.7+/-3.3 days whereas in the early discharge group it was 4.7+/-2.0 days (P<0. 0001) with 73.5% of the patients being discharged within the first 4 days following surgery. The shortening of hospital stay resulted in a mean reduction of costs of pound750/patient. There was no operative mortality (<30 days following surgery) and the incidence of non-fatal perioperative complications were similar in the two groups, with the exception that the incidence of supraventricular arrhythmias was significantly higher in the normal discharge group than in the early discharge group (33% vs. 6.3% respectively; P<0. 0001). These rhythm abnormalities occurred within the first 4 days in 89% of patients following surgery and were the cause of readmission in only one patient in the normal discharge group. There were a total of ten (8.4%) readmissions in the normal discharge group and three (3.8%) in the early discharge group.

CONCLUSION

Shortening the postoperative hospital stay to 4 days following elective coronary bypass surgery appears to be safe and can be a means of reducing the cost of care. This in turn may result in a greater availability of resources and in an effective way of reducing waiting lists.

摘要

目的

早期出院已被提议作为控制心脏手术中不断攀升的医疗费用的一种手段。本研究的目的是调查冠状动脉搭桥手术后缩短住院时间是否安全且具有成本效益。

方法

198例接受择期搭桥手术的患者由两位外科医生在12个月的时间内进行前瞻性研究,但未进行随机分组。所有患者的麻醉和手术治疗相同,只是其中一位外科医生使用间歇性冷晶体心脏停搏液(“正常出院”组;n = 119),另一位使用无心脏停搏液的间歇性缺血(“早期出院”组;n = 79)。在研究之前,两位外科医生均在术后第7 - 8天让患者出院。对于本研究,两位外科医生中的一位采用了在术后第4天让患者出院的新政策(“早期出院”组)。出院标准包括:窦性心律、无发热和伤口感染、常规血液检查正常、胸部X线和心电图满意以及活动自如。

结果

两组的临床特征相同。正常出院组和早期出院组每位患者的移植血管数量分别为2.8±0.8和3.2±1.0,总缺血时间分别为47±13分钟和46±14分钟(各实例中P = 无显著性差异)。正常出院组的平均住院时间为7.7±3.3天,而早期出院组为4.7±2.0天(P < 0.0001),73.5%的患者在术后前4天内出院。住院时间的缩短导致每位患者平均成本降低750英镑。术后30天内无手术死亡,两组非致命围手术期并发症的发生率相似,但正常出院组室上性心律失常的发生率显著高于早期出院组(分别为33%和6.3%;P < 0.0001)。这些节律异常在89%的患者术后前4天内出现,正常出院组仅有1例患者因该原因再次入院。正常出院组共有10例(8.4%)再次入院,早期出院组有3例(3.8%)。

结论

择期冠状动脉搭桥手术后将术后住院时间缩短至4天似乎是安全的,并且可以作为降低护理成本的一种手段。这反过来可能会使资源更易获取,并有效减少等待名单。

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