Rahman J, Rashid M A, Yunus A B, Chowdhury S A, Kabir A, Khan M A, Wajed J
Department of Haematology, Bangabandhu Sheikh Mujib Medical University, Dhaka.
Bangladesh Med Res Counc Bull. 1998 Dec;24(3):79-81.
A married female patient of 36 years with chronic anaemia, because of pure erythroid aplasia with a haemolytic component and hypothyroidism due to antithyroid auto-antibodies, was subsequently discovered as a case of systemic lupus erythematosus (SLE). She was treated with corticosteroid and immunosuppressive therapy and her anaemia was corrected. The response of erythroid aplasia to corticosteroid and other immunosuppressive agents suggests that immunological factors play a role in erythroid aplasia in SLE. The occurrence of red cell aplasia in association with a variety of immune phenomenon supports the concept that in SLE, erythroid aplasia may be of immune aetiology.
一名36岁的已婚女性患者患有慢性贫血，病因是伴有溶血成分的纯红细胞再生障碍以及由抗甲状腺自身抗体导致的甲状腺功能减退，随后被诊断为系统性红斑狼疮（SLE）。她接受了皮质类固醇和免疫抑制治疗，贫血得到纠正。红细胞再生障碍对皮质类固醇和其他免疫抑制剂的反应表明，免疫因素在SLE的红细胞再生障碍中起作用。红细胞再生障碍与多种免疫现象相关的发生情况支持了这样一种概念，即在SLE中，红细胞再生障碍可能是免疫病因。
