Dantchev D
Recent Results Cancer Res. 1976(56):8-16. doi: 10.1007/978-3-642-81049-7_2.
Scanning electron microscopy shows that the thymus cell surface is not smooth but slightly undulated; this type of surface characteristic is found on the cells of several types of T-lymphocyte tumors such as T-cell lymphosarcoma, mycosis fungoides, and T-immunoblastic lymphosarcoma. The cell surface of Frabricius' bursa is covered with numerous short villi. They are found on the cells of several kinds of B-lymphocyte tumors, including B-cell chronic lymphoid leukemia, B-prolymphocytic lymphosarcoma, and B-immunoblastic lymphosarcoma. Mycosis fungoides cells frequently have a characteristic shape. Normal and myeloma plasma cells are similar in shape but their surface is covered with numberous characteristic tiny balls. Immunoblasts are twice the size of so-called small lymphocytes. In the blood and in the lymphocyte population transformed by mitogens, cell surfaces vary from completely smooth (with no undulations as in thymic cells) to villous, with short to very long villi. These variations are visible even when a constant technique and the critical-point drying method are used. Their significance, however, is not known.
扫描电子显微镜显示，胸腺细胞表面并不光滑，而是略有起伏；这种表面特征在几种T淋巴细胞肿瘤的细胞上也能发现，如T细胞淋巴肉瘤、蕈样霉菌病和T免疫母细胞性淋巴肉瘤。法氏囊的细胞表面覆盖着许多短绒毛。在几种B淋巴细胞肿瘤的细胞上也能发现它们，包括B细胞慢性淋巴细胞白血病、B原淋巴细胞性淋巴肉瘤和B免疫母细胞性淋巴肉瘤。蕈样霉菌病细胞通常具有特征性形状。正常浆细胞和骨髓瘤浆细胞形状相似，但它们的表面覆盖着许多特征性的小球。免疫母细胞的大小是所谓小淋巴细胞的两倍。在血液中和由有丝分裂原转化的淋巴细胞群体中，细胞表面各不相同，从完全光滑（没有胸腺细胞那样的起伏）到有绒毛，绒毛由短到非常长。即使使用恒定技术和临界点干燥法，这些变化也是可见的。然而，它们的意义尚不清楚。
