Frisoli Junior A, de Paula A P, Feldman D, Nasri F
Department of Internal Medicine, Universida de Federal de São Paulo, Brazil.
Drugs Aging. 2000 Apr;16(4):313-9. doi: 10.2165/00002512-200016040-00007.
As the world's population ages, chronic and degenerative diseases are rising. This scenario demands the development of new treatment techniques with lower costs, which are as efficient as the existing ones. Hypodermoclysis is the infusion of fluids into the subcutaneous tissue with a butterfly needle. This technique may be used for isotonic fluid replacement and to administer cytosine arabinoside, clodronate, antibiotics and narcotic analgesics. This review evaluates the evidence supporting the use of hypodermoclysis to treat elderly patients with dehydration and patients with terminal cancer, and discusses its indications, adverse effects and perspectives. A MEDLINE search of the last 30 years was done to recover all available literature. Hypodermoclysis therapy is a safe and effective method to provide fluids and narcotic analgesic therapy in elderly patients that are mild and moderate dehydrated and in patients with cancer. It seems a good option to provide antibiotics, but there is a need for more studies to evaluate this indication.
随着世界人口老龄化，慢性和退行性疾病不断增加。这种情况需要开发成本更低且与现有技术同样有效的新治疗技术。皮下输液法是用蝶形针将液体注入皮下组织。该技术可用于等渗液体替代以及给予阿糖胞苷、氯膦酸盐、抗生素和麻醉性镇痛药。本综述评估了支持皮下输液法用于治疗老年脱水患者和晚期癌症患者的证据，并讨论了其适应证、不良反应及前景。对过去30年的医学文献数据库进行检索以获取所有可用文献。皮下输液疗法是为轻度和中度脱水的老年患者以及癌症患者提供液体和麻醉性镇痛治疗的一种安全有效的方法。提供抗生素似乎是个不错的选择，但需要更多研究来评估这一适应证。
