银屑病关节炎中的组织相容性抗原。
Histocompatibility antigens in psoriatic arthritis.
作者信息
Lambert J R, Wright V, Rajah S M, Moll J M
出版信息
Ann Rheum Dis. 1976 Dec;35(6):526-30. doi: 10.1136/ard.35.6.526.
Histocompatibility (HL-A) antigen typing was performed on 82 patients with psoriatic arthritis. The prevalance of HL-AB27 was increased (28%) compared with that in a control group (7-5%), and this was most marked in those with spinal changes. The prevalence in patients with sacroiliitis and syndesmophytes was 75%, with sacroiliitis alone 78%, but with syndesmophytes and normal sacroiliac joints only 36%. The overall prevalence in psoriatic spondylitis was 60%, with a prevalence of 71% in those fulfilling the New York criteria for anklosing spondylitis. The prevalence was not increased in those with only peripheral arthritis (11%). The prevalence of HLA-B13 was decreased in those with psoriatic spondylitis, though this was not statistically significant. The overall prevalence of HLA-BW17 was increased, this being particularly so in those with syndesmophytes, but values were not significant.
对82例银屑病关节炎患者进行了组织相容性（HL - A）抗原分型。与对照组（7.5%）相比，HL - AB27的患病率有所增加（28%），在有脊柱改变的患者中最为明显。骶髂关节炎和韧带骨赘患者的患病率为75%，仅骶髂关节炎患者为78%，但有韧带骨赘且骶髂关节正常的患者仅为36%。银屑病脊柱炎的总体患病率为60%，符合纽约强直性脊柱炎标准的患者患病率为71%。仅患外周关节炎的患者患病率未增加（11%）。银屑病脊柱炎患者中HLA - B13的患病率降低，尽管这在统计学上无显著意义。HLA - BW17的总体患病率增加，在有韧带骨赘的患者中尤其如此，但数值无统计学意义。
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