Bajo J, Moreno-Calvo F J, Martinez-Cortés L, Haya F J, Rayward J
Department of Obstetrics and Gynecology, Hospital Universitario Getafe, 28905 Madrid, Spain.
Hum Reprod. 2000 Jul;15(7):1629-31. doi: 10.1093/humrep/15.7.1629.
In this study a new sign to evaluate the evolution of pregnancy is described: the trophoblastic thickness at the embryonic implantation site. A prospective, observational study of 592 normal pregnancies with no known risk factors was carried out from January 1998 to February 1999. Serial ultrasound scans were performed from week 5 to week 12 of pregnancy. Trophoblastic thickness was measured at the embryonic implantation site to determine the significance of a difference in gestational age in weeks and a trophoblastic thickness of >/=3 mm in predicting poor prognosis in pregnancy outcome. The sensitivity of this sign in the prediction of spontaneous abortion was 82%, the specificity was 93%, the positive predictive value was 63% and the negative predictive value was 97%.
胚胎着床部位的滋养层厚度。1998年1月至1999年2月，对592例无已知危险因素的正常妊娠进行了一项前瞻性观察研究。在妊娠第5周~第12周进行系列超声扫描。测量胚胎着床部位的滋养层厚度，以确定孕周差异以及滋养层厚度≥3 mm对预测妊娠结局不良的意义。该体征预测自然流产的敏感度为82%，特异度为93%，阳性预测值为63%，阴性预测值为97%。
