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钆双胺与稀释碘化造影剂用于腹主动脉和肾动脉成像的可行性比较。

Feasibility of gadodiamide compared with dilute iodinated contrast material for imaging of the abdominal aorta and renal arteries.

作者信息

Spinosa D J, Angle J F, Hagspiel K D, Bissonette E, Conaway M R, Hartwell G D, Matsumoto A H

机构信息

Department of Radiology, University of Virginia Health System, Charlottesville 22908, USA.

出版信息

J Vasc Interv Radiol. 2000 Jun;11(6):733-7. doi: 10.1016/s1051-0443(07)61632-7.

DOI:10.1016/s1051-0443(07)61632-7
PMID:10877418
Abstract

PURPOSE

To determine the quality of digital abdominal angiograms obtained with use of full-strength, intra-arterial gadodiamide compared with similar volumes of half-strength iodinated contrast material for evaluating the abdominal aorta and renal vessels.

MATERIALS AND METHODS

Twenty-five consecutive patients underwent digital subtraction arteriography of the abdominal aorta performed with equal volumes (32 mL) of either half-strength (300 mg/mL iodine) iodinated contrast material or full strength gadodiamide (0.11-0.25 mmol/kg) to evaluate the abdominal aorta and renal arteries. The contrast agent used was not known to the image readers. The abdominal aorta, left and right renal main renal artery, and first and second order segmental branches were graded separately as diagnostic or nondiagnostic by four angiographers.

RESULTS

Images of the abdominal aorta were diagnostic 100% of the time for iodine and gadodiamide, 76% and 80% diagnostic for iodine and gadodiamide in the left main renal artery, respectively; and 100% and 80% diagnostic for iodine and gadodiamide in the right main renal artery, respectively. The first order segmental branches of the right and left renal arteries were graded diagnostic 72% and 56% of the time, respectively, for dilute iodinated contrast material, and 40% and 28% of the time, respectively, for gadodiamide. The second order segmental branches of the right and left kidney were graded diagnostic 24% of the time for iodinated contrast and 8% and 4% of the time, respectively, for gadodiamide.

CONCLUSION

Full-strength, intra-arterial gadodiamide at doses smaller than 0.3 mmol/kg can produce diagnostic images of the abdominal aorta and main renal arteries. However, images of the intrarenal branches are usually not diagnostic.

摘要

目的

比较使用全量动脉内钆双胺与等体积半量碘化造影剂获取的数字腹部血管造影图像质量,以评估腹主动脉和肾血管。

材料与方法

连续25例患者接受腹主动脉数字减影血管造影,分别使用等体积(32 mL)的半量(300 mg/mL碘)碘化造影剂或全量钆双胺(0.11 - 0.25 mmol/kg)来评估腹主动脉和肾动脉。图像阅片者不知道所使用的造影剂。由四位血管造影师分别将腹主动脉、左右肾主肾动脉以及一级和二级节段分支评为诊断性或非诊断性。

结果

腹主动脉图像中,碘化造影剂和钆双胺的诊断率均为100%;左主肾动脉中,碘化造影剂和钆双胺的诊断率分别为76%和80%;右主肾动脉中,碘化造影剂和钆双胺的诊断率分别为100%和80%。左右肾动脉的一级节段分支中,稀释碘化造影剂的诊断率分别为72%和56%,钆双胺的诊断率分别为40%和28%。左右肾的二级节段分支中,碘化造影剂的诊断率为24%,钆双胺的诊断率分别为8%和4%。

结论

剂量小于0.3 mmol/kg的全量动脉内钆双胺可产生腹主动脉和主肾动脉的诊断性图像。然而,肾内分支的图像通常无法用于诊断。

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