Malikides N, Mollison P J, Reid S W, Murray M
University of Glasgow Veterinary School, Bearsden Road, Bearsden, Glasgow, G61 1QH, UK.
Res Vet Sci. 2000 Jun;68(3):275-8. doi: 10.1053/rvsc.2000.0376.
The haematological response of regular, repeated blood harvesting was investigated in 40 Thoroughbred and non-Thoroughbred horses that donate 8 litres of blood every 3 weeks for the purposes of commercial blood production. When this volume of blood was removed on five occasions over 12 weeks, no adverse effect on packed cell volume (PCV), haemoglobin (HB), and red blood cell count (RCC) was observed. Although PCV, RCC and Hb values decreased during the first week after blood collection, followed by a gradual increase in values until the next harvest time, all values remained within published reference ranges. Derived red cell indices [mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH), and mean corpuscular haemoglobin concentration (MCHC)] also remained within reference range. We conclude that the removal of approximately 8 litres of blood (approximately 16 ml kg(-1)or 20 per cent of blood volume for a 500 kg horse) from blood donor horses every 3 weeks allows time for adequate recovery of haematological variables and does not result in adverse haematological changes.
对40匹纯种马和非纯种马进行了研究，这些马为了商业血液生产，每3周捐献8升血液，以调查定期、重复采血的血液学反应。当在12周内分五次采集这个血量时，未观察到对红细胞压积（PCV）、血红蛋白（HB）和红细胞计数（RCC）有不良影响。尽管在采血后的第一周PCV、RCC和Hb值下降，随后这些值逐渐上升直到下一次采血时间，但所有值都保持在已公布的参考范围内。衍生红细胞指数[平均红细胞体积（MCV）、平均红细胞血红蛋白含量（MCH）和平均红细胞血红蛋白浓度（MCHC）]也保持在参考范围内。我们得出结论，每3周从供血马身上采集约8升血液（约16毫升/千克，对于一匹500千克的马约为血容量的20%），能使血液学变量有足够的时间充分恢复，且不会导致不良血液学变化。
