Shimizu N, Minoshima S
Department of Molecular Biology, School of Medicine, Keio University.
Nihon Rinsho. 2000 Jun;58(6):1211-8.
A database of mutations in various cancer-related genes has been constructed and named as KMcancerDB (Keio Mutation DataBase for cancer-related genes). This KMcancerDB utilizes a database software called MutationView which we designed to compile various mutation data and to provide graphical presentation of data analysis through the network using ordinary internet browser softwares such as Netscape. Currently, the KMcancerDB accommodates 1261 mutation data of different genes for cancers in 9 different organs/tissues (breast, stomach, uterus, liver, prostate, colon, ovary, thymus and retinoblastoma). KMcancerDB is accessible through http:¿mutview.dmb.med.keio.ac.jp. OMIM is an important document database for human Mendelian traits and hereditary diseases. The information from OMIM is also used in MutationView/KMcancerDB. Some display windows of OMIM and KMcancerDB are presented.
一个包含各种癌症相关基因突变的数据库已被构建，并命名为KMcancerDB（庆应义塾大学癌症相关基因的突变数据库）。这个KMcancerDB利用了一个名为MutationView的数据库软件，我们设计该软件来汇编各种突变数据，并通过网络使用普通的互联网浏览器软件（如Netscape）提供数据分析的图形展示。目前，KMcancerDB包含了9种不同器官/组织（乳腺、胃、子宫、肝脏、前列腺、结肠、卵巢、胸腺和成视网膜细胞瘤）癌症的1261个不同基因的突变数据。可通过http://mutview.dmb.med.keio.ac.jp访问KMcancerDB。OMIM是人类孟德尔性状和遗传性疾病的重要文献数据库。来自OMIM的信息也用于MutationView/KMcancerDB。展示了一些OMIM和KMcancerDB的显示窗口。
