Chen D
Shanghai Biomaterial Research & Test Center, Shanghai.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2000 Mar;17(1):13-5, 18.
Some properties of the apatite bone cement which is composed of alpha-tricalcium phosphate and hydroxyapatite for use as a biomaterial were investigated. The powder of cement was synthesized from calcium phosphate, calcium carbonate and dicalcium phosphate by solid reaction. Several kinds of citric acid solutions were used for hardening. When the liquid for hardening was 30% (w/w) citric acid solution, the setting time was about six minutes, the compressive strength of hardened bodies was 24.96 MPa, and the solubility was about 1.4 wt%. The compressive strength was increased by the addition of Na or K salt. Especially, when copolymer of acrylic acid/itaconic acid was added to the liquied, the strength was increased about three times, but the setting time was significantly shortened. The results of this study indicate that the apatite bone cement is a potentially highly useful biomaterial for dental and medical applications.
对一种由α-磷酸三钙和羟基磷灰石组成、用作生物材料的磷灰石骨水泥的一些性能进行了研究。水泥粉末通过磷酸钙、碳酸钙和磷酸二钙的固相反应合成。使用了几种柠檬酸溶液进行硬化。当硬化液为30%(w/w)柠檬酸溶液时,凝固时间约为6分钟,硬化体的抗压强度为24.96MPa,溶解度约为1.4wt%。通过添加Na或K盐可提高抗压强度。特别是,当向液体中添加丙烯酸/衣康酸共聚物时,强度提高了约三倍,但凝固时间显著缩短。本研究结果表明,磷灰石骨水泥是一种在牙科和医学应用中潜在非常有用的生物材料。