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Chromosomal proteins in human B and T lymphocytes.

作者信息

Cocco L, Facchini A, Maraldi N M, Capitani S, Manzoli F A

出版信息

Physiol Chem Phys. 1976;8(4):319-25.

PMID:1087980
Abstract

Histones and non-histone chromosomal proteins were characterized in B and T human lymphocytes by means of polyacrylamide disc gel electrophoresis. It was found that while histones do not present appreciable differences in the two examined populations, non-histone chromosomal proteins exhibit distinct electrophoretic profiles. Low molecular weight proteins predominate in B lymphocytes whereas high and intermediate proteins are largely represented in T lymphocytes. The latter proteins may be related to the capability of these resting cells to proliferate under appropriate antigenic stimuli.

摘要

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