Keene J J
Brain Res Bull. 1976 Nov-Dec;1(6):517-22. doi: 10.1016/0361-9230(76)90078-2.
In unanesthetized cerveau isolé rats, brief medial forebrain bundle (MFB) and dorsal midbrain reticular (RET) stimulus trains elicited prolonged MFB unit responses lasting up to ten or more seconds. On the MFB unit responses studied, the effects of MFB and RET stimuli were basically similar, although the stimulations were probably rewarding and aversive respectively. These data agree with the previously reported anatomical localization, in medial regions of thalamus and pallidum, of opposite single cell responses to the behaviorally opposite inputs, and suggest that unit responses to rewarding stimuli should not be characterized as reward-related when aversive stimuli elicit similar responses in the same unit.
在未麻醉的孤立大脑大鼠中，短暂的内侧前脑束（MFB）和中脑背侧网状结构（RET）刺激序列引发了持续长达十秒或更长时间的MFB单位反应延长。在所研究的MFB单位反应中，MFB和RET刺激的效果基本相似，尽管这些刺激可能分别具有奖赏性和厌恶性。这些数据与先前报道的在丘脑和苍白球内侧区域对行为上相反输入的相反单细胞反应的解剖学定位一致，并表明当厌恶性刺激在同一单位引发类似反应时，对奖赏性刺激的单位反应不应被表征为与奖赏相关。
