Gupta D, Agrawal P N, Aggarwal A N, Dhiman R K, Behera D, Chawla Y
Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Trop Gastroenterol. 2000 Apr-Jun;21(2):68-70.
To study the effect of large volume paracentesis (LVP) on pulmonary function in patients with cirrhosis of liver and tense ascites.
Ten patients having alcoholic cirrhosis with ascites were subjected to LVP (mean 6.3 +/- 0.3 L). Pre and post paracentesis spirometry and arterial blood gas analysis were performed and compared.
Baseline mean lung volumes and arterial pO2 were reduced from normal predicted values. Air flow was found normal. After LVP, an increase in absolute values of vital capacity, forced expiratory flow in first second (FEV1) and peak expiratory flow was observed; only the improvement in FEV1 was significant p 0.05). Arterial pO2 also showed significant (p < 0.01) improvement after LVP.
LVP leads to improvement in measured pulmonary function.
研究大量腹腔穿刺放液(LVP)对肝硬化伴张力性腹水患者肺功能的影响。
对10例酒精性肝硬化腹水患者进行大量腹腔穿刺放液(平均6.3±0.3升)。穿刺前后进行肺量计检查和动脉血气分析并比较。
基线平均肺容量和动脉血氧分压低于正常预测值。气流正常。大量腹腔穿刺放液后,肺活量、第一秒用力呼气流量(FEV1)和呼气峰值流量的绝对值增加;只有FEV1的改善具有统计学意义(p<0.05)。大量腹腔穿刺放液后动脉血氧分压也有显著改善(p<0.01)。
大量腹腔穿刺放液可改善所测肺功能。