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[流动单位对青光眼的早期检测——来自10000名受检者的结果]

[Early detection of glaucoma by a mobile unit--results from 10,000 examinees].

作者信息

Kurtz S, Goldenfeld M, Melamed S

机构信息

Sam Rothberg Glaucoma Center, Goldschleger Eye Institute, Sheba Medical Center, Tel Hashomer.

出版信息

Harefuah. 2000 Feb 15;138(4):273-6, 342.

Abstract

Glaucoma, the third leading cause of blindness in the western world, is characterized by painless, gradual loss of visual fields which may lead to severe visual impairment or even blindness. In 4 years of operation of a mobile glaucoma unit for screening and early diagnosis of glaucoma, 10,037 subjects aged 18-95 years were screened (4504 women, 45%); 55% were under 50 years (Graph 1). Ocular hypertension was diagnosed in 8.0%; primary open angle glaucoma (POAG) in 0.8%, with 2/3 already under treatment, the rest newly diagnosed. Pseudo-exfoliative glaucoma was diagnosed in 0.2%; only 2 cases had closed angle glaucoma; 91% of those screened were normal (Fig. 4; age stratification, Graph 3). POAG increased with age, from 0.2% in those under 40 years to 10% in those over 80; POAG was more common in men, but OHT was similar in both sexes (6.0% vs. 5.3%). There was no correlation between incidence of POAG and place of work except in the Sorek Nuclear Center (1.9% vs. 0.8%, p = 0.11). Other conditions significantly more frequent in POAG than normals were diabetes mellitus (x 2.5), systemic hypertension (x 4), myopia (x 2) and history of intraocular surgery (x 6).

摘要

青光眼是西方世界致盲的第三大主要原因,其特征是视野无痛性逐渐丧失,这可能导致严重视力损害甚至失明。在一个流动青光眼筛查和早期诊断单元运行的4年里,对10,037名年龄在18至95岁的受试者进行了筛查(4504名女性,占45%);55%的受试者年龄在50岁以下(图1)。诊断出高眼压症的比例为8.0%;原发性开角型青光眼(POAG)为0.8%,其中三分之二已经在接受治疗,其余为新诊断病例。剥脱性青光眼诊断率为0.2%;仅2例为闭角型青光眼;91%的筛查者结果正常(图4;年龄分层,图3)。POAG随年龄增长而增加,从40岁以下人群中的0.2%增至80岁以上人群中的10%;POAG在男性中更常见,但高眼压症在两性中相似(分别为6.0%和5.3%)。除了索雷克核中心外,POAG发病率与工作地点之间没有相关性(1.9%对0.8%,p = 0.11)。POAG患者中明显比正常人更常见的其他情况包括糖尿病(2.5倍)、系统性高血压(4倍)、近视(2倍)和眼内手术史(6倍)。

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