Ling G N, Ochsenfeld M M
Physiol Chem Phys. 1976;8(5):389-95.
At 25 degrees C, frog sartorius muslces rapidly gained Na+ and lost K+ in iodoacetamide and pure nitrogen. Beginning at normal levels, the concentrations of these ions in the cells reached those in the surrounding Ringer solution in 140 min. Yet during that time the Na+ efflux rate showed no sign of the slowing down demanded by Na-pump theory. The data support the view that maintenance and alterations of N1+ levels in frog muslce cells reflect adsorption on protein sites and the solubility property of bulk phase water and are independent of the rate at which Na+ leaves the cell surface.
在25摄氏度时,青蛙缝匠肌在碘乙酰胺和纯氮气环境中迅速摄取钠离子并丢失钾离子。从正常水平开始,细胞内这些离子的浓度在140分钟内达到周围任氏液中的浓度。然而在这段时间里,钠离子外流速率并未显示出钠泵理论所要求的减缓迹象。这些数据支持这样一种观点,即青蛙肌肉细胞中钠离子水平的维持和变化反映了在蛋白质位点上的吸附以及体相水的溶解性,并且与钠离子离开细胞表面的速率无关。