Izuta S, Yaku H, Kiyonari Y, Maekawa N, Obara H
Department of Anesthesiology, Kobe University School of Medicine.
Masui. 2000 Jun;49(6):649-51.
A 46-year-old female with mitochondrial encephalomyopathy underwent the replacement of right femur head under continuous epidural anesthesia. Considering that this disease is a neuromuscular disorder, general anesthesia should be avoided. In addition, the patients with mitochondrial encephalomyopathy tend to show increased concentrations of lactate and pyruvate caused by perioperative stress. Use of lactated Ringer's solution may elevate these concentrations. We managed this patient uneventfully with continuous epidural anesthesia and the use of acetated Ringer's solution during the perioperative period. We consider that continuous epidural anesthesia is useful for a patient with mitochondrial encephalomyopathy.
一名46岁的线粒体脑肌病女性患者在连续硬膜外麻醉下行右侧股骨头置换术。鉴于该疾病是一种神经肌肉疾病，应避免全身麻醉。此外，线粒体脑肌病患者在围手术期应激状态下往往会出现乳酸和丙酮酸浓度升高。使用乳酸林格氏液可能会使这些浓度升高。我们在围手术期通过连续硬膜外麻醉和使用醋酸林格氏液顺利处理了该患者。我们认为连续硬膜外麻醉对线粒体脑肌病患者有用。
