Zenz W, Trop M, Kollaritsch H, Reinthaler F
Universitätsklinik für Kinder- und Jugendheilkunde Graz.
Wien Klin Wochenschr. 2000 May 19;112(10):459-61.
Increasing tourism and growing numbers of immigrants from malaria-endemic countries are leading to a higher importation rate of rare tropical disorders in European countries. We describe, to the best of our knowledge, the first case of connatal malaria in Austria. The patient is the first child of a 24 year old mother who was born in Ghana and immigrated to Austria one and a half years before delivery. She did not stay in an endemic region during this period and did not show fever or any other signs of malaria. The boy was healthy for the first six weeks of his life. In the 8th week of life he was admitted to our hospital due to persistent fever of unknown origin. On physical examination he showed only mild splenomegaly. Routine laboratory testing revealed mild hemolytic anemia with a hemoglobin value of 8.3 g/l. In the blood smear Plasmodium falciparum and Plasmodium malariae were detected. Oral therapy with quinine hydrochloride was successful and blood smears became negative for Plasmodia within 6 days. This case shows that congenital malaria can occur in children of clinically healthy women who were born in malaria-endemic areas even one and a half year after they have immigrated to non-endemic regions.
旅游业的发展以及来自疟疾流行国家的移民数量不断增加，导致欧洲国家罕见热带疾病的输入率上升。据我们所知，我们描述了奥地利首例先天性疟疾病例。患者是一名24岁母亲的第一个孩子，母亲出生在加纳，在分娩前一年半移民到奥地利。在此期间，她没有去过疟疾流行地区，也没有发烧或任何其他疟疾症状。这个男孩在出生后的前六周很健康。在出生后的第8周，他因不明原因的持续发热被收治入院。体格检查仅发现轻度脾肿大。常规实验室检查显示轻度溶血性贫血，血红蛋白值为8.3 g/l。在血涂片检查中检测到恶性疟原虫和间日疟原虫。口服盐酸奎宁治疗成功，6天内血涂片疟原虫检测呈阴性。该病例表明，先天性疟疾可发生在出生于疟疾流行地区的临床健康女性的子女中，即使她们移民到非流行地区一年半后也可能出现。
