Liu G, Zhang S D, Xia S Q, Ding Z K
Institute of Pharmacology and Toxicology, Academy of Military Medical Science, Beijing, China.
Bioorg Med Chem Lett. 2000 Jun 19;10(12):1361-3. doi: 10.1016/s0960-894x(00)00241-9.
Solid-phase synthetic method of muramyl dipeptide derivatives is reported. A diverse library of muramyl dipeptides could be potentially synthesized by acylation, reductive alkylation, sulfonamide formation, urea formation, N-alkylation, amine addition, or component Ugi reactions based on this method for drug screening.
