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Synthesis of biologically active biotinylated muramyl dipeptides.生物活性生物素化的 muramyl 二肽的合成。
Bioorg Med Chem Lett. 2010 Oct 15;20(20):6061-3. doi: 10.1016/j.bmcl.2010.08.056. Epub 2010 Aug 17.
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Synthesis of biotinylated muramyl tripeptides with NOD2-stimulating activity.具有 NOD2 刺激活性的生物素化 muramyl 三肽的合成。
Bioorg Med Chem Lett. 2011 Jun 1;21(11):3362-6. doi: 10.1016/j.bmcl.2011.04.005. Epub 2011 Apr 9.
3
Lipophilic Muramyl Dipeptide-Antigen Conjugates as Immunostimulating Agents.亲脂性胞壁酰二肽-抗原缀合物作为免疫刺激剂
ChemMedChem. 2016 Jan 19;11(2):190-8. doi: 10.1002/cmdc.201500196. Epub 2015 Jun 9.
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Synthesis of Diverse N-Substituted Muramyl Dipeptide Derivatives and Their Use in a Study of Human NOD2 Stimulation Activity.多种N-取代的胞壁酰二肽衍生物的合成及其在人类NOD2刺激活性研究中的应用。
Chemistry. 2015 Aug 17;21(34):11984-8. doi: 10.1002/chem.201501557. Epub 2015 Jul 16.
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Further Insights on Structural Modifications of Muramyl Dipeptides to Study the Human NOD2 Stimulating Activity.进一步探讨 Muramyl Dipeptides 的结构修饰以研究人类 NOD2 刺激活性。
Chem Asian J. 2020 Nov 16;15(22):3836-3844. doi: 10.1002/asia.202001003. Epub 2020 Oct 20.
6
Structure-activity relationship in NOD2 agonistic muramyl dipeptides.NOD2 激动型 muramyl dipeptides 的结构-活性关系。
Eur J Med Chem. 2024 May 5;271:116439. doi: 10.1016/j.ejmech.2024.116439. Epub 2024 Apr 20.
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Design, synthesis and biological evaluation of novel lipophilic 2, 5-disubstituted tetrazole analogues of muramyl dipeptide as NOD2 agonists.新型亲脂性 2,5-二取代四唑类似物作为 NOD2 激动剂的设计、合成及生物评价。
Bioorg Med Chem. 2023 Jun 6;88-89:117296. doi: 10.1016/j.bmc.2023.117296. Epub 2023 Apr 29.
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Surface calreticulin mediates muramyl dipeptide-induced apoptosis in RK13 cells.表面钙网蛋白介导胞壁酰二肽诱导的RK13细胞凋亡。
J Biol Chem. 2005 Jun 10;280(23):22425-36. doi: 10.1074/jbc.M413380200. Epub 2005 Apr 6.
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The innate immune protein Nod2 binds directly to MDP, a bacterial cell wall fragment.天然免疫蛋白 Nod2 直接结合 MDP，一种细菌细胞壁片段。
J Am Chem Soc. 2012 Aug 22;134(33):13535-7. doi: 10.1021/ja303883c. Epub 2012 Aug 13.
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Discovery of Nanomolar Desmuramylpeptide Agonists of the Innate Immune Receptor Nucleotide-Binding Oligomerization Domain-Containing Protein 2 (NOD2) Possessing Immunostimulatory Properties.发现具有免疫刺激特性的天然免疫受体核苷酸结合寡聚化结构域蛋白 2（NOD2）的纳米摩尔脱甲酰基肽激动剂。
J Med Chem. 2018 Apr 12;61(7):2707-2724. doi: 10.1021/acs.jmedchem.7b01052. Epub 2018 Mar 22.
引用本文的文献
1
Structure-activity relationship in NOD2 agonistic muramyl dipeptides.NOD2 激动型 muramyl dipeptides 的结构-活性关系。
Eur J Med Chem. 2024 May 5;271:116439. doi: 10.1016/j.ejmech.2024.116439. Epub 2024 Apr 20.
2
Chemical immunology: Recent advances in tool development and applications.化学免疫学：工具开发与应用的最新进展
Cell Chem Biol. 2024 Mar 13. doi: 10.1016/j.chembiol.2024.02.006.
3
A synthetic pathogen mimetic molecule induces a highly amplified synergistic immune response activation of multiple signaling pathways.一种合成病原体模拟分子可诱导高度放大的协同免疫反应——激活多种信号通路。
Chem Sci. 2021 Apr 1;12(19):6646-6651. doi: 10.1039/d1sc00964h.
4
Synthesis of Bacterial-Derived Peptidoglycan Cross-Linked Fragments.细菌衍生肽聚糖交联片段的合成。
J Org Chem. 2020 Dec 18;85(24):16243-16253. doi: 10.1021/acs.joc.0c01852. Epub 2020 Oct 27.
5
Revisiting peptidoglycan sensing: interactions with host immunity and beyond.重新审视肽聚糖感知：与宿主免疫的相互作用及其他。
Chem Commun (Camb). 2020 Nov 11;56(87):13313-13322. doi: 10.1039/d0cc02605k. Epub 2020 Oct 15.
6
Synthesis and Application of Methyl N,O-Hydroxylamine Muramyl Peptides.甲基 N,O-羟氨酰基肽的合成与应用。
Chembiochem. 2019 Jun 3;20(11):1369-1375. doi: 10.1002/cbic.201800731. Epub 2019 Mar 21.
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From bacterial killing to immune modulation: Recent insights into the functions of lysozyme.从细菌杀伤到免疫调节：溶菌酶功能的最新见解
PLoS Pathog. 2017 Sep 21;13(9):e1006512. doi: 10.1371/journal.ppat.1006512. eCollection 2017 Sep.
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Crohn's Disease Variants of Nod2 Are Stabilized by the Critical Contact Region of Hsp70.热休克蛋白70的关键接触区域可稳定克罗恩病相关的Nod2变异体。
Biochemistry. 2017 Aug 29;56(34):4445-4448. doi: 10.1021/acs.biochem.7b00470. Epub 2017 Aug 15.
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Membrane Association Dictates Ligand Specificity for the Innate Immune Receptor NOD2.膜结合决定天然免疫受体NOD2的配体特异性。
ACS Chem Biol. 2017 Aug 18;12(8):2216-2224. doi: 10.1021/acschembio.7b00469. Epub 2017 Jul 25.
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Molecular Recognition of Muramyl Dipeptide Occurs in the Leucine-rich Repeat Domain of Nod2.胞壁酰二肽的分子识别发生在Nod2富含亮氨酸的重复结构域中。
ACS Infect Dis. 2017 Apr 14;3(4):264-270. doi: 10.1021/acsinfecdis.6b00154. Epub 2016 Oct 31.
本文引用的文献
1
How the noninflammasome NLRs function in the innate immune system.无炎体型 NOD 样受体（NLRs）在固有免疫系统中的作用机制。
Science. 2010 Jan 15;327(5963):286-90. doi: 10.1126/science.1184004.
2
Recognition of microorganisms and activation of the immune response.微生物的识别与免疫反应的激活。
Nature. 2007 Oct 18;449(7164):819-26. doi: 10.1038/nature06246.
3
Unravelling the pathogenesis of inflammatory bowel disease.揭示炎症性肠病的发病机制。
Nature. 2007 Jul 26;448(7152):427-34. doi: 10.1038/nature06005.
4
Pathogen recognition and innate immunity.病原体识别与固有免疫
Cell. 2006 Feb 24;124(4):783-801. doi: 10.1016/j.cell.2006.02.015.
5
Signalling pathways and molecular interactions of NOD1 and NOD2.NOD1和NOD2的信号通路及分子相互作用
Nat Rev Immunol. 2006 Jan;6(1):9-20. doi: 10.1038/nri1747.
6
Membrane recruitment of NOD2 in intestinal epithelial cells is essential for nuclear factor-{kappa}B activation in muramyl dipeptide recognition.NOD2在肠道上皮细胞中的膜募集对于胞壁酰二肽识别中的核因子-κB激活至关重要。
J Cell Biol. 2005 Jul 4;170(1):21-6. doi: 10.1083/jcb.200502153.
7
NOD-LRR proteins: role in host-microbial interactions and inflammatory disease.NOD样受体蛋白：在宿主-微生物相互作用及炎症性疾病中的作用
Annu Rev Biochem. 2005;74:355-83. doi: 10.1146/annurev.biochem.74.082803.133347.
8
Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract.Nod2对肠道固有免疫和适应性免疫的调控
Science. 2005 Feb 4;307(5710):731-4. doi: 10.1126/science.1104911.
9
Peptidoglycan molecular requirements allowing detection by Nod1 and Nod2.肽聚糖的分子要求，使其能够被Nod1和Nod2检测到。
J Biol Chem. 2003 Oct 24;278(43):41702-8. doi: 10.1074/jbc.M307198200. Epub 2003 Jul 18.
10
NODs: intracellular proteins involved in inflammation and apoptosis.核苷酸结合寡聚化结构域蛋白：参与炎症和细胞凋亡的细胞内蛋白质。
Nat Rev Immunol. 2003 May;3(5):371-82. doi: 10.1038/nri1086.
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