Kotani K, Hidaka I, Yamamoto Y, Ozono S
Department of Precision Engineering, Graduate School of Engineering, University of Tokyo, Japan.
Methods Inf Med. 2000 Jun;39(2):153-6.
We evaluated the respiratory modulation of heart rate, i.e., respiratory sinus arrhythmia (RSA), with respect to respiratory phase derived from an analytic signal from the lung volume curve, during spontaneous breathing and paced breathing with different patterns. The magnitudes and waveforms of RSA in the phase domain were similar regardless of breathing pattern, even including spontaneous breathing. An examination of the occurrence of heart beats with respect to the respiratory phase revealed that synchronized patterns recently reported in the literature (Nature 392: 239, 1998) were observed during paced breathing with breath holding periods whereby the respiratory phase advanced more slowly. It was concluded that the phase domain approach might be useful in extracting RSA during spontaneous breathing and for elucidating detailed mechanisms for RSA. However, the use of this technique for studies investigating cardio-respiratory coupling should be approached cautiously, as the results may be influenced by breathing patterns.
我们评估了心率的呼吸调制，即呼吸性窦性心律不齐（RSA），它与源自肺容积曲线解析信号的呼吸相位有关，涵盖了不同模式的自主呼吸和定频呼吸。无论呼吸模式如何，包括自主呼吸，RSA在相位域中的幅度和波形都是相似的。对心跳相对于呼吸相位的发生情况进行检查发现，在有屏气期的定频呼吸期间，观察到了文献（《自然》392: 239, 1998）中最近报道的同步模式，此时呼吸相位推进得更慢。得出的结论是，相位域方法可能有助于在自主呼吸期间提取RSA，并阐明RSA的详细机制。然而，在用于研究心肺耦合的研究中使用该技术时应谨慎，因为结果可能会受到呼吸模式的影响。
