Kagami S, Nakayama T, Shiraishi T, Yatani R
Clinical Laboratory, Tsu Seikyo Hospital.
Rinsho Byori. 2000 May;48(5):473-8.
A 59-year-old woman with leukorrhea. Aspiration smears were obtained from the uterine cavity. The dominant cellular components were fibrogenic sarcomatous cells, which had ill-defined lacy cytoplasm and a single nucleus with finely granular chromatin. There were occasional naked giant cells, and intracytoplasmic eosinophilic granules. Another infrequent cellular component was adenocarcinoma cells. Histopathologically, adenocarcinoma and spindle cell sarcoma were equivalently identified. Twenty-two cases of homologous carcinosarcoma of the uterine corpus were reviewed cytologically in Japan. Cytodiagnosis before treatment was positive for malignancy of carcinosarcoma in 28.6%. Characteristic cytological findings of this case were the presence of flat sheets of atypical cells with broad cytoplasm. These findings suggest epithelial features. However, the finely granular chromatin pattern and smooth nuclear membrane indicate sarcomatous cells.
一名59岁有白带异常的女性。从子宫腔获取了抽吸涂片。主要细胞成分是纤维生成性肉瘤样细胞，其细胞质呈边界不清的花边状，有单个细胞核，染色质呈细颗粒状。偶尔可见裸核巨细胞和胞质内嗜酸性颗粒。另一种少见的细胞成分是腺癌细胞。组织病理学检查发现，腺癌细胞和梭形细胞肉瘤同等存在。对日本22例子宫体同源性癌肉瘤进行了细胞学回顾分析。治疗前的细胞诊断显示，癌肉瘤恶性的阳性率为28.6%。该病例的特征性细胞学表现为存在具有宽大细胞质的非典型细胞扁平片。这些表现提示上皮特征。然而，细颗粒状染色质模式和平滑的核膜提示为肉瘤样细胞。
