Holmström G, Thorén K
Department of Ophthalmology, Academic Hospital, Uppsala, Sweden.
Acta Ophthalmol Scand. 2000 Jun;78(3):348-53. doi: 10.1034/j.1600-0420.2000.078003348.x.
The study aimed to evaluate the ocular manifestations in patients with incontinentia pigmenti (IP).
Thirty patients from different parts of Sweden participated. Orthoptic and ocular examinations were performed as well as evaluation of refraction and visual acuity.
Ocular manifestations, probably associated with IP, were found in 77% (23/30) of the patients. Thirteen had serious or vision-threatening eye manifestations in one eye, of whom 7 were totally blind in that eye from retinal detachments. Ten patients had minor retinal and/or corneal changes.
Ocular lesions in patients with IP may be serious and lead to blindness because of retinal disease. Ophthalmological follow-up is essential in the neonatal period and such a programme is recommended.
本研究旨在评估色素失禁症（IP）患者的眼部表现。
来自瑞典不同地区的30名患者参与了研究。进行了斜视及眼科检查，以及屈光和视力评估。
77%（23/30）的患者发现了可能与IP相关的眼部表现。13名患者一只眼睛有严重或威胁视力的眼部表现，其中7名因视网膜脱离导致该眼完全失明。10名患者有轻微的视网膜和/或角膜变化。
IP患者的眼部病变可能很严重，并因视网膜疾病导致失明。新生儿期进行眼科随访至关重要，建议开展此类项目。
