滑石粉肉芽肿病。HIV患者间质性肺疾病的鉴别诊断。

Talc granulomatosis. A differential diagnosis of interstitial lung disease in HIV patients.

作者信息

Nan D N, Fernández-Ayala M, Iglesias L, García-Palomo D, Parra J A, Fariñas M C

机构信息

Infectious Diseases Unit, Department of Internal Medicine, Universitario Marqués de Valdecilla, Universidad de Cantabria, Santander, Spain.

出版信息

Chest. 2000 Jul;118(1):258-60. doi: 10.1378/chest.118.1.258.

DOI:10.1378/chest.118.1.258

PMID:10893392

Abstract

Consumers of adulterated drugs may present with talc-induced interstitial lung disease. A transbronchial biopsy specimen showing granulomas with intracellular talc crystals is necessary to confirm this diagnosis. In patients infected with HIV, such a condition can be indistinguishable at first glance from opportunistic infections or other pulmonary diseases. A case is presented of a seropositive patient whose chest radiographs showed a diffuse interstitial pattern.

摘要

使用掺假药物的消费者可能会出现滑石粉诱发的间质性肺病。要确诊此病，经支气管活检标本显示含有细胞内滑石晶体的肉芽肿是必要的。对于感染了HIV的患者，这种病症乍一看可能与机会性感染或其他肺部疾病难以区分。本文介绍了一例血清学阳性患者，其胸部X光片显示为弥漫性间质模式。