Szarfman A, Khoury E L, Cossio P M, Arana R M, Kagan I G
Am J Trop Med Hyg. 1975 Jan;24(1):19-24. doi: 10.4269/ajtmh.1975.24.19.
The specificity of a circulating antibody observed in American trypanosomiasis and reacting with endocardium, blood vessels, and the interstitium of striated muscle (EVI factor) was evaluated in the indirect fluorescent antibody test with 60 sera from patients with malaria, leishmaniasis, echinococcosis, amebiasis, African trypanosomiasis, toxoplasmosis, and trichinosis, collected from areas where Chagas' disease is not endemic. Two sera, 1 from a patient with Plasmodium falciparum malaria and 1 from a patient with a relapse pretreatment post kala-azar dermal leishmaniasis, were positive for the EVI factor. In the leishmaniasis group, 3 of 8 sera reacted with 0ovine, murine, and human skeletal muscle. In this reaction, which differs from the EVI test, the sarcolemma and the intracellular structures were stained.
在美国锥虫病中观察到的一种循环抗体的特异性，该抗体与心内膜、血管及横纹肌间质发生反应（EVI因子），采用间接荧光抗体试验对60份来自疟疾、利什曼病、棘球蚴病、阿米巴病、非洲锥虫病、弓形虫病和旋毛虫病患者的血清进行评估，这些血清采自恰加斯病非流行地区。两份血清呈EVI因子阳性，一份来自恶性疟患者，另一份来自黑热病皮肤利什曼病复发前经治疗的患者。在利什曼病组中，8份血清中有3份与绵羊、小鼠和人类骨骼肌发生反应。在该反应中，肌膜和细胞内结构被染色，这与EVI试验不同。
