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[躯体肌肉急性代谢损害中的局灶性肌原纤维紊乱]

[Focal myofibrillar disorganization in acute metabolic impairment of somatic musculature].

作者信息

Tsellarius S F, Tsellarius Iu G

出版信息

Biull Eksp Biol Med. 1975 Jan;79(1):71-4.

PMID:1089435
Abstract

Skeletal muscles of rats and rabbits were studied by the target electron microscoptic and polarization-optic methods after administration of toxic substances and experimental acute ischemia of the extremities. Two types of foci of the myofibrillae disaggregation were described along with contracture injuries. The first occurred on the basis of relaxation and was expressed in total dysaggregation and lysis of myofibrillae; with the second type lysis occurred in the partially contracted fibers and began in the I-discs leading to diastasis of A-discs. The first type of the foci is characteristic chiefly of the white fibers, and the second one--of the red.

摘要

采用靶电子显微镜和偏振光学方法,对给予有毒物质后及实验性急性肢体缺血的大鼠和家兔骨骼肌进行了研究。除挛缩损伤外,还描述了两种肌原纤维解体灶。第一种发生在松弛的基础上,表现为肌原纤维完全解体和溶解;第二种类型的溶解发生在部分收缩的纤维中,始于I带,导致A带分离。第一种类型的病灶主要见于白肌纤维,第二种则见于红肌纤维。

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