Usuki K, Sekiyama M, Shimada T, Shimada S, Kanzaki T
Department of Dermatology, Kagoshima University Faculty of Medicine, Japan.
Dermatology. 2000;200(4):324-7. doi: 10.1159/000018397.
Pityriasis rubra pilaris (PRP) is reported to respond poorly to cyclosporin A (CsA).
We attempted to determine the efficacy of CsA in the treatment of classic adult-type PRP.
Three patients with classic adult-type PRP were treated with 5 mg/kg/day CsA.
A sustained clinical response was achieved within 2-4 weeks of therapy. Relapses were noted when the CsA dose was decreased to 1.2 mg/kg/day.
CsA should be considered in the treatment of classical adult-type PRP.
据报道,红皮病型毛发红糠疹(PRP)对环孢素A(CsA)反应不佳。
我们试图确定CsA治疗经典成人型PRP的疗效。
3例经典成人型PRP患者接受5mg/kg/天的CsA治疗。
治疗2 - 4周内取得持续临床缓解。当CsA剂量降至1.2mg/kg/天时出现复发。
经典成人型PRP的治疗应考虑使用CsA。