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颌骨成釉细胞瘤

Ameloblastoma of the jaws.

作者信息

Munir M

机构信息

Department of Otolaryngology, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia.

出版信息

Gan To Kagaku Ryoho. 2000 May;27 Suppl 2:261-7.

Abstract

Ameloblastoma is a histologically benign tumor derived from odontogenic apparatus. The tumor can infiltrate into surrounding tissues. Although it is benign, it presents symptoms of a malignant tumor, such as infiltration into the lungs, pleura, regional and distant metastases, orbit, base of skull, brain and has resulted in death. It also has a high incidence of recurrences, the existence of regional or distant metastasis, showing a microscopic pattern of ameloblastic carcinoma with cytologic features of an increasing nuclear/cytoplastic ratio, nuclear hyperchromatism, and the presence of mitosis. We report a study of 12 patients of ameloblastoma of the jaws between January 1992 and December 1996 consisting of 8 affected in the mandible and 4 in the maxilla. One patient with a tumor in the maxilla was excluded from this study, due to a different histological and clinical behaviour of the ameloblastoma.

摘要

成釉细胞瘤是一种组织学上良性的肿瘤,起源于牙源性器官。该肿瘤可浸润周围组织。尽管它是良性的,但却表现出恶性肿瘤的症状,如浸润至肺部、胸膜、局部及远处转移、眼眶、颅底、脑部,甚至导致死亡。其复发率也很高,存在局部或远处转移,呈现出成釉细胞癌的微观模式,具有核/质比增加、核深染以及有丝分裂等细胞学特征。我们报告了一项对1992年1月至1996年12月期间12例颌骨成釉细胞瘤患者的研究,其中8例在下颌骨,4例在上颌骨。由于该上颌骨肿瘤的组织学和临床行为不同,一名上颌骨肿瘤患者被排除在本研究之外。

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