Huang I-Yueh, Lai Sheng-Tsung, Chen Chung-Ho, Chen Chun-Ming, Wu Chung-Wei, Shen Yee-Hsiung
Department of Oral and Maxillofacial Surgery, Chon-ho Memorial Hospital, and School of Dentistry, College of Dental Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 Oct;104(4):478-85. doi: 10.1016/j.tripleo.2007.01.033. Epub 2007 May 24.
The purpose of this study was to report experience in the treatment of ameloblastoma in Taiwanese children and to discuss the treatment regimen.
Fifteen patients, all younger than 18 years of age, with a diagnosis of ameloblastoma in our department between January 1991 and December 2004 were selected for study. Data included sex, age at surgery, tumor type, size and site of lesion, primary surgical methods, use of adjuvant therapy, complications, recurrences, and course of follow-up.
Ages ranged from 9 to 17 (average was 13.7 years). Nine were male, 6 were female; the sex ratio was 1.5:1. Fourteen lesions were in the mandible (1 in the symphysis, 13 in the mandibular posterior area) and only 1 was in the maxilla. The size of the lesions ranged from 4 x 2.5 cm to 8 x 8 cm. Clinical typing included 8 unicystic type, 3 multicystic type, and 4 solid types. Of the histologic types, 5 were plexiform, 3 were mixed type, and 3 were acanthomatous type. Complications included numbness of the lower lip and contour defect of the face. Three cases (20%) were recurrent, and 1 patient had 2 recurrences.
Good results can be achieved in the treatment of ameloblastoma in children using conservative surgery. In the event of recurrence, a second surgery can be successful. Patient compliance and careful follow-up are important.
本研究旨在报告台湾儿童成釉细胞瘤的治疗经验并探讨治疗方案。
选取1991年1月至2004年12月间在我科诊断为成釉细胞瘤的15例18岁以下患者进行研究。数据包括性别、手术年龄、肿瘤类型、病变大小和部位、初次手术方法、辅助治疗的使用、并发症、复发情况及随访过程。
年龄范围为9至17岁(平均13.7岁)。男性9例,女性6例;性别比为1.5:1。14处病变位于下颌骨(1例位于正中联合,13例位于下颌后部区域),仅1例位于上颌骨;病变大小范围为4×2.5厘米至8×8厘米。临床分型包括8例单囊性、3例多囊性和4例实性;组织学类型中,5例为丛状型,3例为混合型,3例为棘皮瘤型。并发症包括下唇麻木和面部轮廓缺损。3例(20%)复发,1例患者复发2次。
采用保守手术治疗儿童成釉细胞瘤可取得良好效果。复发时二次手术可成功。患者的依从性和仔细的随访很重要。