Lagziel A, DeNise S, Hanotte O, Dhara S, Glazko V, Broadhead A, Davoli R, Russo V, Soller M
Department of Genetics, Hebrew University of Jerusalem, Israel.
Anim Genet. 2000 Jun;31(3):210-3. doi: 10.1046/j.1365-2052.2000.00622.x.
Information is presented on the frequency of the Msp I (-) allele in the third intron of the bovine growth hormone gene in a large number of cattle breeds. Consideration of the breed frequencies in relation to their geographic origin shows a low frequency for breeds originating in Northern Europe, moderate frequencies for breeds originating in Eastern Europe or the countries surrounding the Mediterranean basin, and very high frequencies for breeds originating in the Indian subcontinent. Consideration of breed frequencies in relation to breed type, shows low to moderate frequencies for the humpless breeds, high frequencies for the humped breeds. Various explanations for this distribution are discussed, among them the possibility that the Msp I (-) allele originated in the Bos indicus breeds of the Indian subcontinent, from which it diffused through the humpless Bos taurus breeds of Eastern Europe, the Mediterranean basin, eventually reaching Western, Northern Europe, Western Africa in low frequencies.
文中呈现了大量牛品种中牛生长激素基因第三内含子Msp I (-)等位基因的频率信息。考虑到品种频率与其地理起源的关系，北欧起源的品种频率较低，东欧或地中海盆地周边国家起源的品种频率适中，而印度次大陆起源的品种频率非常高。考虑到品种频率与品种类型的关系，无峰品种的频率低至适中，有峰品种的频率高。文中讨论了这种分布的各种解释，其中包括Msp I (-)等位基因起源于印度次大陆的瘤牛品种的可能性，它从那里通过东欧、地中海盆地的无峰普通牛品种扩散，最终以低频率到达西欧、北欧、西非。
