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儿茶酚胺能神经元中促黄体生成素释放激素(LH-RH)的缺失。

Absence of luteinizing hormone-releasing hormone (LH-RH) from catecholaminergic neurons.

作者信息

Kizer J S, Arimura A, Schally A V, Brownstein M J

出版信息

Endocrinology. 1975 Feb;96(2):523-5. doi: 10.1210/endo-96-2-523.

Abstract

6-Hydroxy-dopamine was administered into the third ventricle of adult male rats. After 2 successive 250 mug doses of 6-OH-dopamine, the levels of norepinephrine and dopamine in the median eminence and arcuate nucleus fell to 15-20% of the control value. The amount of luteinizing hormone releasing hormone (LH-RH) in these same hypothalamic areas, however, was unchanged. It is concluded that LH-RH containing cells are distinct from catecholaminergic neurons.

摘要

将6-羟基多巴胺注入成年雄性大鼠的第三脑室。连续两次给予250微克剂量的6-羟基多巴胺后,正中隆起和弓状核中去甲肾上腺素和多巴胺的水平降至对照值的15 - 20%。然而,这些相同下丘脑区域中促黄体生成素释放激素(LH-RH)的量未发生变化。得出的结论是,含LH-RH的细胞与儿茶酚胺能神经元不同。

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