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大肠杆菌对5'-单磷酸腺苷的摄取

Uptake of adenosine 5'-monophosphate by Escherichia coli.

作者信息

Yagil E, Beacham I R

出版信息

J Bacteriol. 1975 Feb;121(2):401-5. doi: 10.1128/jb.121.2.401-405.1975.

DOI:10.1128/jb.121.2.401-405.1975
PMID:1089626
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC245943/
Abstract

Adenosine 5'-monophosphate is dephosphorylated before its uptake by cells of Escherichia coli. This is demonstrated by using a radioactive double-labeled culture, and with a 5'-nucleotidase-deficient, mutant strain. The adenosine formed is further phosphorolyzed to adenine as a prerequisite for its uptake and incorporation. The cellular localization of the enzymes involved in the catabolism of adenosine 5'-monophosphate is discussed.

摘要

5'-单磷酸腺苷在被大肠杆菌细胞摄取之前会发生去磷酸化。这通过使用放射性双标记培养物以及一个缺乏5'-核苷酸酶的突变菌株得以证明。形成的腺苷会进一步磷酸解为腺嘌呤，这是其摄取和掺入的前提条件。文中还讨论了参与5'-单磷酸腺苷分解代谢的酶在细胞内的定位。

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本文引用的文献

1
The metabolism of exogenously supplied nucleotides by Escherichia coli.大肠杆菌对外源供应核苷酸的代谢。
J Biol Chem. 1960 Feb;235:457-65.
2
THE UTILIZATION OF GLUCOSE 6-PHOSPHATE BY GLUCOKINASELESS AND WILD-TYPE STRAINS OF ESCHERICHIA COLI.葡萄糖激酶缺陷型和野生型大肠杆菌菌株对6-磷酸葡萄糖的利用情况
Proc Natl Acad Sci U S A. 1964 Nov;52(5):1207-13. doi: 10.1073/pnas.52.5.1207.
3
ACTIVE TRANSPORT OF L-ALPHA-GLYCEROPHOSPHATE IN ESCHERICHIA COLI.大肠杆菌中L-α-甘油磷酸的主动运输
J Biol Chem. 1964 Sep;239:3098-105.
4
INDUCTION OF REPLICATION BY THYMINE STARVATION AT THE CHROMOSOME ORIGIN IN ESCHERICHIA COLI.大肠杆菌中染色体起源处胸腺嘧啶饥饿诱导复制
J Mol Biol. 1964 Aug;9:288-307. doi: 10.1016/s0022-2836(64)80208-4.
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STUDIES ON THE GLUCOSE-TRANSPORT SYSTEM IN ESCHERICHIA COLI WITH ALPHA-METHYLGLUCOSIDE AS SUBSTRATE.以α-甲基葡萄糖苷为底物对大肠杆菌葡萄糖转运系统的研究。
Biochim Biophys Acta. 1963 Nov 15;78:505-15. doi: 10.1016/0006-3002(63)90912-0.
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Biochem J. 1959 Oct;73(2):264-70. doi: 10.1042/bj0730264.
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FEBS Lett. 1971 Aug 1;16(2):77-80. doi: 10.1016/0014-5793(71)80336-8.
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The relationship of adenosine and inosine transport in Escherichia coli.大肠杆菌中腺苷和肌苷转运的关系。
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On the catabolism of deoxyribonucleosides in cells and cell extracts of Escherichia coli.关于大肠杆菌细胞及细胞提取物中脱氧核糖核苷的分解代谢
Eur J Biochem. 1968 Nov;6(3):432-42. doi: 10.1111/j.1432-1033.1968.tb00465.x.