Cho K O, Park N Y, Kang M I, Umemura K, Itakura C
Vet Pathol. 2000 Jul;37(4):340-3. doi: 10.1354/vp.37-4-340.
Ganglion cysts were diagnosed in a 4-month-old male Afghan Hound. Grossly, the subcutaneous ovoid cysts around the caudal right elbow joint and left ischiatic tuberosity had abundant mucinous fluid and internal folding. The lesions recurred twice around the elbow joint after surgical removal. Neither cyst communicated with the joint cavity. Histologically, the cyst wall consisted of inner myxomatous and outer immature connective tissue. Some parts of the cyst wall had various stages of myxoid metaplasia of collagen tissue leading to new cyst formation. Ultrastructural study revealed that cells in the myxoid metaplastic lesion had well-developed cytoplasmic secretory elements, including abundant rough endoplasmic reticulum, Golgi apparatus, and many smooth-walled vesicles. These ganglion cysts apparently resulted from the metaplasia of fibroblasts to secreting cells.
一只4个月大的雄性阿富汗猎犬被诊断出患有腱鞘囊肿。大体上，右肘后关节和左坐骨结节周围的皮下椭圆形囊肿含有大量黏液性液体且内部有褶皱。手术切除后，肘关节周围的病变复发了两次。两个囊肿均未与关节腔相通。组织学上，囊肿壁由内部黏液瘤样和外部未成熟结缔组织组成。囊肿壁的某些部分有胶原组织黏液样化生的不同阶段，导致新囊肿形成。超微结构研究显示，黏液样化生病变中的细胞具有发育良好的细胞质分泌成分，包括丰富的粗面内质网、高尔基体和许多光滑壁小泡。这些腱鞘囊肿显然是由成纤维细胞化生为分泌细胞所致。
