Léger J M, Chassande B
Fédération de Neurologie, Bâtiment Mazarin, Hôpital de la Salpêtrière, 47, boulevard de l'Hôpital, Paris.
Ann Med Interne (Paris). 2000 May;151 Suppl 1:1S19-23.
Chronic immune-mediated polyneuropathies encompass chronic inflammatory demyelinating polyneuropathies, polyneuropathies associated with monoclonal gammopathy and multifocal motor neuropathy with persistent conduction blocks. Their diagnosis is made on clinical, electrophysiological and sometimes immunochemical and pathological criteria. The efficacy of short-term treatments (corticosteroids, plasma exchanges, intravenous immunoglobulins) depends on the type of the polyneuropathy, but these treatments may sometimes lead to prolonged improvement. The efficacy of long-term treatments needs further evaluation.
慢性免疫介导性多发性神经病包括慢性炎症性脱髓鞘性多发性神经病、与单克隆丙种球蛋白病相关的多发性神经病以及伴有持续性传导阻滞的多灶性运动神经病。其诊断基于临床、电生理标准，有时还包括免疫化学和病理学标准。短期治疗（皮质类固醇、血浆置换、静脉注射免疫球蛋白）的疗效取决于多发性神经病的类型，但这些治疗有时可能会带来长期改善。长期治疗的疗效需要进一步评估。
