Nieuwland W, Berkhuysen M A, van Veldhuisen D J, Brügemann J, Landsman M L, van Sonderen E, Lie K I, Crijns H J, Rispens P
Department of Cardiology/Thoraxcenter, University Hospital Groningen, The Netherlands.
J Am Coll Cardiol. 2000 Jul;36(1):202-7. doi: 10.1016/s0735-1097(00)00692-6.
We sought to study the influence of frequency of exercise training during cardiac rehabilitation on functional capacity (i.e., peak oxygen consumption [VO2] and ventilatory anaerobic threshold [VAT]) and quality of life (QoL).
Although the value of cardiac rehabilitation is now well established, the influence of the different program characteristics on outcome has received little attention, and the effect of frequency of exercise training is unclear. Functional capacity is regularly evaluated by peak VO2 but parameters of submaximal exercise capacity such as VAT should also be considered because submaximal exercise capacity is especially important in daily living.
Patients with coronary artery disease (n = 130, 114 men; mean age 52 +/- 9 years) were randomized to either a high- or low-frequency program of six weeks (10 or 2 exercise sessions per week of 2 h, respectively). Functional capacity and QoL were assessed before and after cardiac rehabilitation. Global costs were also compared.
Compared with baseline, mean exercise capacity increased in both programs: for high- and low-frequency, respectively: peak VO2 = 15% and 12%, Wmax = 18% and 12%, VAT = 35% and 12% (all p < 0.001). However, when the programs were compared, only VAT increased significantly more during the high-frequency program (p = 0.002). During the high-frequency program, QoL increased slightly more, and more individuals improved in subjective physical functioning (p = 0.014). We observed superiority of the high-frequency program, especially in younger patients. Mean costs were estimated at 4,455 and 2,273 Euro, respectively, for the high- and low-frequency programs.
High-frequency exercise training is more effective in terms of VAT and QoL, but peak VO2 improves equally in both programs. Younger patients seem to benefit more from the high-frequency training.
我们试图研究心脏康复期间运动训练频率对功能能力（即峰值耗氧量[VO₂]和通气无氧阈[VAT]）及生活质量（QoL）的影响。
尽管心脏康复的价值现已得到充分确立，但不同项目特征对结果的影响却很少受到关注，且运动训练频率的效果尚不清楚。功能能力通常通过峰值VO₂进行评估，但诸如VAT等次最大运动能力参数也应予以考虑，因为次最大运动能力在日常生活中尤为重要。
将130例冠心病患者（114例男性；平均年龄52±9岁）随机分为六周的高频或低频方案组（分别为每周10次或2次，每次2小时的训练课程）。在心脏康复前后评估功能能力和QoL。还比较了总体成本。
与基线相比，两个方案组的平均运动能力均有所提高：高频组和低频组的峰值VO₂分别提高了15%和12%，最大摄氧量（Wmax）分别提高了18%和12%，VAT分别提高了35%和12%（所有p<0.001）。然而，当比较两个方案组时，仅高频方案组的VAT增加更为显著（p = 0.002）。在高频方案组中，QoL的提高略多，且更多个体在主观身体功能方面有所改善（p = 0.014）。我们观察到高频方案组具有优势，尤其是在年轻患者中。高频和低频方案组的平均成本分别估计为4455欧元和2273欧元。
高频运动训练在VAT和QoL方面更有效，但两个方案组的峰值VO₂改善程度相同。年轻患者似乎从高频训练中获益更多。
