Ashida Y, Ohgi S, Kuroda H, Ishiguro S, Hamasaki T, Miyasaka S, Ono K
Second Department of Surgery, Faculty of Medicine, Tottori University, 36-1 Nishi-cho, Yonago, Tottori 683-8504, Japan.
Ann Thorac Cardiovasc Surg. 2000 Jun;6(3):161-6.
Between January 1980 and January 1998, implantation of a permanent pacemaker (PP) was performed in 22 patients (6.7%) following 327 acquired valvular surgeries. The indications for implantation of a PP were bradycardia with atrial fibrillation in 12 cases, sick sinus syndrome in 7 cases and complete atrioventricular block in 3 cases. These patients received an implantation after surgery for mitral valvular disease in 14 cases, aortic valvular disease in 3 cases and combined valvular disease in 5 cases. These cases were also concomitant with a tricuspid valve annuloplasty in 6 cases for secondary regurgitation and with a maze procedure in 4 cases. For the purpose of this study, these patients were compared to patients who did not require implantation of a PP after surgery. Univariate analysis showed the significant factors to be female gender (p = 0. 041), preoperative atrial fibrillation (p = 0.013), redo cardiac surgery (p < 0.0001), and the use of blood cardioplegia (p = 0.003). There were no differences in valvular disease, age at the last valvular operation, addition of tricuspid valve annuloplasty, extracorporeal circulation times, or aortic cross-clamp times between those patients with and those without PP. Among these factors, logistic regression analysis showed female gender, redo surgery and the use of blood cardioplegia to be more significant predictors for the requirement of PP after acquired valvular disease operation. Maze procedure was not a significant predictor for the requirement of PP after surgery.
1980年1月至1998年1月期间,在327例后天性瓣膜手术后,22例患者(6.7%)植入了永久性起搏器(PP)。植入PP的指征为:12例伴有心房颤动的心动过缓、7例病态窦房结综合征和3例完全性房室传导阻滞。这些患者在二尖瓣疾病手术后植入14例,主动脉瓣疾病手术后植入3例,联合瓣膜疾病手术后植入5例。其中6例因继发性反流同时行三尖瓣环成形术,4例同时行迷宫手术。为了本研究的目的,将这些患者与术后不需要植入PP的患者进行比较。单因素分析显示,显著因素为女性(p = 0.041)、术前心房颤动(p = 0.013)、再次心脏手术(p < 0.0001)和使用血液停搏液(p = 0.003)。植入PP的患者与未植入PP的患者在瓣膜疾病、最后一次瓣膜手术时的年龄、是否加做三尖瓣环成形术、体外循环时间或主动脉阻断时间方面没有差异。在这些因素中,逻辑回归分析显示,女性、再次手术和使用血液停搏液是后天性瓣膜疾病手术后需要植入PP的更显著预测因素。迷宫手术不是术后需要植入PP的显著预测因素。