Shah S N, Tomohiro T, Ogawa Y, Kodaka M, Okuno H
Biomolecules Department, National Institute of Bioscience and Human-Technology, Tsukuba, Ibaraki, Japan.
Lipids. 2000 Jun;35(6):689-91. doi: 10.1007/s11745-000-0574-2.
A novel lipid analog with two long alkyl (C16) chains, an aspartate skeleton, a connecting alkyl (C8) chain, and 2-nitrophenol trigger group is synthesized by an efficient synthetic route, which can induce liposome fusion at physiological pH.
通过一种高效合成路线合成了一种新型脂质类似物，其具有两条长烷基（C16）链、一个天冬氨酸骨架、一条连接烷基（C8）链和2-硝基苯酚触发基团，该脂质类似物能够在生理pH值下诱导脂质体融合。
