Maisch B, Portig I, Ristic A, Hufnagel G, Pankuweit S
Department of Internal Medicine-Cardiology, Philipps-University Marburg, Germany.
Herz. 2000 May;25(3):200-9. doi: 10.1007/s000590050007.
This article reviews the current state of consensus reached for the diagnosis of myocarditis and dilated cardiomyopathy on the basis of conventional histopathological and immunohistochemical methods for inflammatory infiltrates in addition to molecular biological methods for persistence of viral genome in endomyocardial biopsies. Additionally, a brief overview is presented stating the current knowledge on effector mechanisms of the immune system in myocarditis and dilated cardiomyopathy.
本文回顾了基于传统组织病理学和免疫组织化学方法检测炎症浸润以及分子生物学方法检测心内膜心肌活检中病毒基因组持续性,在心肌炎和扩张型心肌病诊断方面所达成的共识现状。此外,还简要概述了目前关于心肌炎和扩张型心肌病中免疫系统效应机制的知识。