Mogyorósy G, Belicza E, Karácsonyi T, Szúcs E
Debreceni Egyetem, Orvos- és Egészségtudományi Centrum, Altalános Orvostudományi Kar, Gyermekklinika.
Orv Hetil. 2000 Jun 4;141(23):1287-92.
The incidence of congenital heart diseases was evaluated in the period 1994-1998. The number of those who went through therapeutic intervention and those infants dying of congenital heart disease were also assessed. Data were collected retrospectively. During the study period 26,932 live-births occurred in Hajdú-Bihar county and 421 congenital heart disease were diagnosed, 81% of whom were diagnosed under the age of one year. The most frequent diseases were secundum type atrial septal defect, ventricular septal defect and patent ductus arteriosus. 121 therapeutic procedures were performed (109 operations and 12 interventional heart catheterizations). 41 interventions occurred under the age of one and 13 before the age of 28 days. The mean age of children older than 1 year was 6 years at the time of the operation or interventional catheterization. The overall postoperative mortality within 30 days was 8.3%. During the study period 28 infants with significant heart disease died, 20 of whom also had an associated disease (most frequently prematurity). For congenital heart disease 4.5 operations or interventional heart catheterizations were required/1000 live births. The higher rate of diagnosed congenital heart disease is due to the development in diagnostic techniques, especially to Doppler-echocardiography. Owing to the operational waiting list the children's age at the time of operation is higher than optimal. The mortality among infants with heart disease is influenced by many factors, that is why stepping forward is a complex task in this field.
对1994年至1998年期间先天性心脏病的发病率进行了评估。还对接受治疗性干预的人数以及死于先天性心脏病的婴儿数量进行了评估。数据采用回顾性收集。在研究期间,豪伊杜-比豪尔县有26,932例活产,诊断出421例先天性心脏病,其中81%在1岁前被诊断出来。最常见的疾病是继发孔型房间隔缺损、室间隔缺损和动脉导管未闭。共进行了121次治疗程序(109次手术和12次心脏介入导管插入术)。41次干预在1岁前进行,13次在28天前进行。1岁以上儿童在进行手术或介入导管插入术时的平均年龄为6岁。术后30天内的总体死亡率为8.3%。在研究期间,28例患有严重心脏病的婴儿死亡,其中20例还患有其他相关疾病(最常见的是早产)。每1000例活产中,先天性心脏病需要进行4.5次手术或心脏介入导管插入术。先天性心脏病诊断率较高归因于诊断技术的发展,尤其是多普勒超声心动图。由于手术等待名单,儿童手术时的年龄高于最佳年龄。患有心脏病的婴儿死亡率受多种因素影响,因此在这一领域取得进展是一项复杂的任务。