Pass H I, Crawford F A, Sade R M, Assey M E, Usher B W
Am Surg. 1984 Jan;50(1):36-9.
From January 1972 to April 1982, 125 adults underwent operation for congenital heart disease at the Medical University of South Carolina. Age ranged from 18 to 73 years, with an average age of 31 years. A variety of defects were seen. Atrial septal defect (59 patients), ventricular septal defect (15 patients), patent ductus arteriosus (14 patients), tetralogy of Fallot (14 patients), and coarctation of the aorta (9 patients) were the most common. There were 48 men and 77 women in the study. Most patients presented with recent onset of dyspnea on exertion or at rest, but 16 patients were asymptomatic. Eight patients died after surgery for an overall operative mortality rate of 6 per cent. The most common postoperative complication was arrhythmia (13 patients, 10%). Despite recent advances in the diagnosis and treatment of congenital heart disease in infants, a significant number of patients apparently escape detection and first present with congenital heart disease as adults. Prompt diagnosis and surgical intervention will usually produce excellent results and relief of symptoms in these patients.
1972年1月至1982年4月,125名成年人在南卡罗来纳医科大学接受了先天性心脏病手术。年龄范围为18岁至73岁,平均年龄为31岁。发现了多种缺陷。房间隔缺损(59例)、室间隔缺损(15例)、动脉导管未闭(14例)、法洛四联症(14例)和主动脉缩窄(9例)最为常见。研究中有48名男性和77名女性。大多数患者表现为近期出现的劳力性或静息性呼吸困难,但16例患者无症状。8例患者术后死亡,总体手术死亡率为6%。最常见的术后并发症是心律失常(13例,10%)。尽管近年来婴儿先天性心脏病的诊断和治疗取得了进展,但仍有相当数量的患者显然未被发现,首次以成人先天性心脏病就诊。及时诊断和手术干预通常会在这些患者中产生优异的效果并缓解症状。