由母体淋巴细胞植入伴迪格奥尔格综合征引发的移植物抗宿主病的罕见并发情况。
An unusual concurrence of graft versus host disease caused by engraftment of maternal lymphocytes with DiGeorge anomaly.
作者信息
Ocejo-Vinyals J G, Lozano M J, Sánchez-Velasco P, Escribano de Diego J, Paz-Miguel J E, Leyva-Cobián F
机构信息
Servicio de Inmunología, Hospital Universitario "Marqués de Valdecilla", Instituto Nacional de la Salud, 39008 Santander, Spain.
出版信息
Arch Dis Child. 2000 Aug;83(2):165-9. doi: 10.1136/adc.83.2.165.
Abstract
We describe a girl with DiGeorge anomaly and normal cytogenetic and molecular studies, whose clinical course was complicated by graft versus host disease caused by intrauterine materno-fetal transfusion, and several immunohematological alterations including a monoclonal gammapathy of undetermined significance (first IgG, which subsequently changed to IgM). The main clinical features and pathological findings are discussed.
摘要
我们描述了一名患有DiGeorge异常且细胞遗传学和分子学研究结果正常的女孩，其临床病程因宫内母胎输血导致的移植物抗宿主病以及包括意义未明的单克隆丙种球蛋白病（最初为IgG，随后转变为IgM）在内的多种免疫血液学改变而变得复杂。文中讨论了主要临床特征和病理发现。
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