Lorenz S, Maier C, Segerer H, Landthaler M, Hohenleutner U
Klinik und Poliklinik für Dermatologie, Universitätsklinikum Regensburg.
Hautarzt. 2000 Jun;51(6):396-400. doi: 10.1007/s001050051140.
To prospectively survey skin lesions in a large group of newborns, as no such study has as yet been performed in Germany.
PATIENTS/METHODS: In a prospective study, we examined one thousand newborn babies twelve to 120 hours old.
In 59.7%, one or more skin lesions could be detected, some of which were only transient. Noticeable differences from other studies included a higher incidence of congenital melanocytic nevi (6%) and port wine stains (2.8%). Instead of the usual male:female ratio of 1:2 we found a 1:1 ratio for port wine stains. Toxic erythema of the newborn and milia were less frequent than in other studies.
With a frequency of 37.2%, vascular lesions such as nevus flammeus and hemangioma are the most common skin lesions in newborns. Our study found a higher incidence of congenital melanocytic nevi than reported in literature. An associated of skin lesions and maternal smoking during pregnancy was not detected.
为对大量新生儿的皮肤病变进行前瞻性调查,因为德国尚未开展过此类研究。
患者/方法:在一项前瞻性研究中,我们检查了1000名出生12至120小时的新生儿。
59.7%的新生儿可检测到一处或多处皮肤病变,其中一些病变只是暂时的。与其他研究的显著差异包括先天性黑素细胞痣(6%)和葡萄酒色斑(2.8%)的发病率较高。葡萄酒色斑的男女比例不是常见的1:2,而是1:1。新生儿中毒性红斑和粟丘疹比其他研究中的发病率更低。
葡萄酒色痣和血管瘤等血管性病变是新生儿中最常见的皮肤病变,发病率为37.2%。我们的研究发现先天性黑素细胞痣的发病率高于文献报道。未检测到皮肤病变与孕期母亲吸烟之间的关联。