Zidan J, Stayerman C, Turani H
Oncology Unit and Pathology Institute, Rebecca Sieff Hospital, Safed.
Harefuah. 1998 Mar 1;134(5):353-5, 423.
Secondary malignancy is a well-recognized complication of radiation therapy. The risk of postirradiation sarcoma in long-term follow-up is 0.03-0.8%. We report a case of radiation-induced perisacral angiosarcoma 6 years after pelvic irradiation for sigmoid cancer in a 77-year-old man. The tumor was diagnosed postmortem and was locally advanced and metastatic. He died 6 months after onset of symptoms. This case demonstrates the importance of long-term follow-up in those given radiotherapy.