Rath E, Shelef I, Avinoah E, Lichtman Y, Levy O, Atar D
Harefuah. 1998 May 1;134(9):695-7, 750.
The dramatic course of necrotizing soft tissue infection represents a medical emergency, since it is limb- and life-threatening. Most necrotizing soft tissue infections are caused by mixed aerobic and anaerobic Gram-negative and Gram-positive organisms. Most case have been reported in immuno-compromised hosts after penetrating trauma or surgery. We describe a unique series of cases of necrotizing soft tissue infection. The mainstay of treatment is early and daily debridement of devitalized tissue and broad-spectrum antibiotics. Hyperbaric oxygen therapy should be considered.
坏死性软组织感染的急剧病程是一种医疗急症,因为它会危及肢体和生命。大多数坏死性软组织感染是由需氧菌和厌氧菌混合的革兰氏阴性菌和革兰氏阳性菌引起的。大多数病例报告发生在穿透性创伤或手术后的免疫功能低下宿主中。我们描述了一系列独特的坏死性软组织感染病例。治疗的主要方法是早期每日对失活组织进行清创,并使用广谱抗生素。应考虑高压氧治疗。