Marszał M, Bielecki K
Państwowego Szpitala Klinicznego Nr 1 im. Prof. W. Orłowskiego w Warszawie.
Wiad Lek. 1998;51(1-2):64-70.
Nectrotizing fasciitis is a mixed infection of skin and subcutaneous tissue with a characteristic clinical and pathological appearance. Necrotizing soft tissue infections, caused by aerobic, anaerobic and mixed bacterial flora are an increasing problem in medical and surgical practice. The apparently wide variety of these infections is systematized. Etiology and bacteriology are discussed, as the role of surgery, antibiotics and hyperbaric chamber in the treatment of the infections. Early and radical surgical excision of all affected tissue is the treatment of choice. Adjuvant hyperbaric oxygen appears to be important in refractory progressive bacterial gangrene. A combination of hyperbaric oxygen, surgical treatment and antibiotics gives the lowest mortality and morbidity in gas gangrene compared with other treatment modifications. Extensive clinical experience shows the efficacy of these treatment protocols.
坏死性筋膜炎是皮肤和皮下组织的混合感染，具有特征性的临床和病理表现。由需氧菌、厌氧菌及混合菌群引起的坏死性软组织感染，在医学和外科实践中是一个日益严重的问题。这些感染看似种类繁多，但已被系统化。本文讨论了病因学和细菌学，以及手术、抗生素和高压氧舱在这些感染治疗中的作用。早期彻底手术切除所有受感染组织是首选治疗方法。辅助性高压氧在难治性进行性细菌性坏疽中似乎很重要。与其他治疗方法相比，高压氧、手术治疗和抗生素联合使用在气性坏疽中死亡率和发病率最低。广泛的临床经验表明了这些治疗方案的有效性。
