Pérez-Perdomo R V, Rodríguez-Figueroa L
Department of Biostatistics and Epidemiology, Graduate School of Public Health, University of Puerto Rico, San Juan 00936-5067.
P R Health Sci J. 2000 Jun;19(2):123-9.
To evaluate and describe the characteristics and incidence of pediatric (< 20 years) cancer in Puerto Rico between 1980-1991.
A descriptive study of all new childhood cancer cases among residents of Puerto Rico reported to the Cancer Registry between the years 1980 and 1991 was conducted. The distribution of cases was described by age, gender, place of residence, histology, last date known to be alive, and stage of disease. Incidence rates and standardized incidence rates by age were calculated.
A total of 1,823 new pediatric cases were reported from 1980 through 1991. Over half were males, and 52.2% were aged < 10 years. Most cases resided in urban areas. The most frequent histologic types were leukemia (31.0%), lymphomas and other reticulo-endothelial neoplasms (16.2%), and brain, central nervous system, and intracranial and intraspinal neoplasms (16.0%). The most frequent type of tumor was acute lymphocytic leukemia (22.0%). Although the overall distribution of most neoplasms was similar between genders, a higher proportion of lymphomas was reported among males, and there were significantly more carcinomas among girls. The largest increase in the age-adjusted incidence rate between periods (1980-84 and 1985-89) occurred in the 5-9 age group.
Overall, these findings are consistent with previous studies in USA. However, there were some differences in the distribution of histologic types when compared with similar studies in other countries, and with the results of the National Cancer Institute's Surveillance, Epidemiology and End Results (SEER) Program. Factors such as differences in diagnostic capabilities among countries must be taken into consideration.
评估并描述1980年至1991年间波多黎各20岁以下儿童癌症的特征及发病率。
对1980年至1991年间向癌症登记处报告的波多黎各居民中所有新的儿童癌症病例进行描述性研究。通过年龄、性别、居住地、组织学类型、已知存活的最后日期以及疾病分期来描述病例分布情况。计算年龄别发病率和标准化发病率。
1980年至1991年共报告了1823例新的儿童病例。超过半数为男性，52.2%的患者年龄小于10岁。大多数病例居住在城市地区。最常见的组织学类型为白血病（31.0%）、淋巴瘤及其他网状内皮系统肿瘤（16.2%）、脑、中枢神经系统及颅内和椎管内肿瘤（16.0%）。最常见的肿瘤类型是急性淋巴细胞白血病（22.0%）。尽管大多数肿瘤的总体分布在性别之间相似，但男性中淋巴瘤的报告比例较高，女性中的癌明显更多。各时期（1980 - 1984年和1985 - 1989年）年龄调整发病率增幅最大的是5 - 9岁年龄组。
总体而言，这些发现与美国先前的研究一致。然而，与其他国家的类似研究以及美国国立癌症研究所的监测、流行病学和最终结果（SEER）计划的结果相比，组织学类型的分布存在一些差异。各国诊断能力差异等因素必须予以考虑。
