Strong W B, Rao P S, Steinbaugh M
South Med J. 1975 Mar;68(3):319-27.
This review article stresses the importance of prevention in the reduction of the incidence of artherosclerotic disease, especially coronary heart disease. Evidence accumulated from autopsy studies, animal experimentation, and long-term epidemiologic studies supports the concept that atherosclerosis has its inception in childhood. Adult programs designed to change life styles and attitudes or reverse morphologic changes appear doomed to failure. Therefore, if nutritional, physical activity, and smoking habits are to be altered, it is essential to begin these efforts in infancy and childhood.
这篇综述文章强调了预防在降低动脉粥样硬化疾病尤其是冠心病发病率方面的重要性。来自尸检研究、动物实验和长期流行病学研究积累的证据支持了动脉粥样硬化始于儿童期的概念。旨在改变生活方式和态度或逆转形态学改变的成人项目似乎注定要失败。因此，如果要改变营养、身体活动和吸烟习惯，在婴儿期和儿童期就开始这些努力至关重要。
