Pediatrics. 1998 Jan;101(1 Pt 1):141-7.
This updated statement reviews the scientific justification for the recommendations of dietary changes in all healthy children (a population approach) and a strategy to identify and treat children who are at highest risk for the development of accelerated atherosclerosis in early adult life (an individualized approach). Although the precise fraction of risk for future coronary heart disease conveyed by elevated cholesterol levels in childhood is unknown, clear epidemiologic and experimental evidence indicates tha the risk is significant. Diet changes that lower fat, saturated fat, and cholesterol intake in children and adolescents can be applied safely and acceptably, resulting in improved plasma lipid profiles that, if carried into adult life have the potential to reduce atherosclerotic vascular disease.
本更新声明回顾了针对所有健康儿童进行饮食改变建议的科学依据(群体方法),以及识别和治疗在成年早期发生加速动脉粥样硬化风险最高的儿童的策略(个体化方法)。虽然儿童期胆固醇水平升高所传递的未来冠心病风险的确切比例尚不清楚,但明确的流行病学和实验证据表明该风险很大。降低儿童和青少年脂肪、饱和脂肪和胆固醇摄入量的饮食改变可以安全且可接受地实施,从而改善血脂谱,如果持续到成年期,有可能降低动脉粥样硬化性血管疾病的发生风险。