血小板肝素中和因子（血小板第4因子）
Platelet heparin-neutralizing factor (platelet factor 4).
作者信息
Lüscher E F, Käser-Glanzman R
出版信息
Thromb Diath Haemorrh. 1975 Feb 28;33(1):66-72.
PMID:1091019
Abstract
The heparin-neutralizing platelet factor (PF4) is released from platelets under the influence of inducers of aggregation and nucleotide-release in the form of a high-molecular weight complex. The heparin-neutralizing activity is carried by a basic protein of molecular weight 29,700, four of which combine with a proteoglycan carrier, which in turn consists of 4 chondroitin sulfate A residues and a peptide moiety.
摘要
肝素中和性血小板因子（PF4）在聚集诱导剂和核苷酸释放诱导剂的影响下，以高分子量复合物的形式从血小板中释放出来。肝素中和活性由一种分子量为29,700的碱性蛋白质承担，该蛋白质的四个分子与一个蛋白聚糖载体结合，而该蛋白聚糖载体又由4个硫酸软骨素A残基和一个肽部分组成。
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