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外耳道鳞状细胞癌:一种分期系统的评估

Squamous cell carcinoma of the external auditory canal: an evaluation of a staging system.

作者信息

Moody S A, Hirsch B E, Myers E N

机构信息

Department of Otolaryngology, University of Pittsburgh Medical Center, Pennsylvania, USA.

出版信息

Am J Otol. 2000 Jul;21(4):582-8.

Abstract

OBJECTIVE

The study was conducted to review a staging system proposed by the University of Pittsburgh for temporal bone cancer and to evaluate survival status according to stage, treatment, and certain prognostic factors.

STUDY DESIGN

The study was a retrospective case review.

SETTING

The study was conducted at a tertiary care medical center and specialty hospital.

PATIENTS

Thirty-two patients with primary squamous cell carcinoma of the external auditory canal were studied.

INTERVENTION

All patients underwent surgery of the temporal bone. Radiotherapy was given depending on tumor stage and histopathologic findings.

MAIN OUTCOME MEASURES

The 2-year survival rates of patients undergoing surgical resection with or without adjuvant radiotherapy.

RESULTS

The 2-year survival rates for primary squamous cell carcinoma of the temporal bone were as follows: T1 lesions 100%, T2 80%, T3 50%, and T4 7%. Survival for T3 tumors was 75% with postoperative radiotherapy, compared with 0% with surgery alone.

CONCLUSIONS

The 2-year survival data directly correlated with the staging system. The use of adjuvant radiotherapy increased survival rate in patients with a T3 lesion.

摘要

目的

本研究旨在回顾匹兹堡大学提出的颞骨癌分期系统,并根据分期、治疗方法及某些预后因素评估生存状况。

研究设计

本研究为回顾性病例分析。

研究地点

研究在一家三级医疗中心及专科医院进行。

患者

对32例外耳道原发性鳞状细胞癌患者进行了研究。

干预措施

所有患者均接受了颞骨手术。根据肿瘤分期及组织病理学检查结果给予放疗。

主要观察指标

接受手术切除且有或无辅助放疗患者的2年生存率。

结果

颞骨原发性鳞状细胞癌的2年生存率如下:T1期病变为100%,T2期为80%,T3期为50%,T4期为7%。T3期肿瘤术后放疗的生存率为75%,单纯手术的生存率为0%。

结论

2年生存数据与分期系统直接相关。辅助放疗可提高T3期病变患者的生存率。

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