Dunsdon R M, Greening J R, Jones P S, Jordan S, Wilson F X
Department of Medicinal Chemistry, Roche Discovery Welwyn, Welwyn Garden City, Herts, UK.
Bioorg Med Chem Lett. 2000 Jul 17;10(14):1577-9. doi: 10.1016/s0960-894x(00)00284-5.
Use of a resin bound diol as a boronic acid protecting group has been developed to allow the parallel synthesis of potent inhibitors of the hepatitis C virus NS3 serine proteinase.
已开发出使用树脂结合二醇作为硼酸保护基，以实现丙型肝炎病毒NS3丝氨酸蛋白酶强效抑制剂的平行合成。
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